A prospective randomized trial of N-acetyl cysteine administration during cold preservation of the donor liver for transplantation
Aims: N-acetyl cysteine (NAC), an anti oxidant and a glutathione precursor, is effective in ameliorating liver injury of Tylenol overdose.There is experimental evidence that it also reduces ischemia reperfusion (I/R) injury.This clinical study was undertaken to study the effect of NAC administered in the donor operation.Methods: 22 patients were ra